Hair loss is a relatively common condition which could heavily impact one’s quality of life, self-confidence and psychoemotional well-being.
Vitamin supplements and hair supplements are gaining popularity recently as a way of preventing hair loss.
Vitamin D is one of the main vitamins and hormones that plays an important role in dermatotherapeutics due to its anti-inflammatory, immunomodulatory properties, and it’s regulating effects on keratinocyte differentiation and proliferation.
Vitamin D also affects the hair cycle, and its role in hair loss is being constantly evaluated in dermatology research. Multiple studies have investigated the role of vitamin D in hair loss, as a supplement and potential treatment modality to be offered.
In today’s blog we review if the use of Vitamin D as a daily supplement for patients with hair loss is backed by science.
Vitamin D is involved in various pathways associated with growth and differentiation of hair follicles. Majority of the studies published on vitamin D, do report an inverse relationship between serum vitamin D levels and non-scarring alopecias. Vitamin D deficiency has also been shown to be associated with scarring alopecia.
With non-scarring alopecia, the hair follicle remains intact and the hair shaft is either not produced, not produced correctly, or the follicle itself is miniaturized. With this type of alopecia, regrowth of hair is possible although might be hard to achieve.
Scarring alopecia on the other hand is mostly caused by permanent destruction of hair follicles due to inflammation, progressive deposition of collagen, and destruction of hair follicle stem cell (HFSC).
Even though there are studies linking vitamin D deficiency to scarring alopecia and non- Scarring alopecia, the evidence is inconclusive regarding the benefit of vitamin D administration/supplement in correcting hair loss in patients that lack vitamin D.
Considering the inconclusive evidence, further studies are needed before vitamin D can be routinely recommended as a treatment modality for patients with hair loss.